TOPLINE:
Recorded long COVID was more prevalent in men with type 2 diabetes (T2D) than in matched non-T2D control individuals, whereas the opposite was seen for women with T2D. Overall recorded long COVID rates were similar for men and women with T2D. Younger age, female sex, mixed ethnicity and higher body mass index (BMI) were all associated with a greater likelihood of developing long COVID.
METHODOLOGY:
- A retrospective cohort study of 3087 people with a recorded diagnosis of type 1 diabetes (T1D) and 29,700 with T2D who had proven SARS-CoV-2 infection from the electronic health Greater Manchester Care Record data.
- They were matched 1:3 with control individuals without diabetes, ie, 14,077 with T1D and 119,951 with T2D.
TAKEAWAY:
- For T1D, diagnosis of long COVID and/or referral to a long COVID clinic were lower than among their matched control individuals (0.33% vs 0.48%; P = .009).
- In T2D, the prevalence of long COVID diagnosis/referral was not significantly different vs control individuals (0.53% vs 0.54%).
- Among men, those with T2D had a higher prevalence of long COVID than control individuals (0.54% vs 0.46%; P = .008).
- In women, long COVID was more prevalent among those without T2D (0.61% vs 0.53%; P = .007).
- In a logistic regression, younger age, female sex, mixed ethnicity, and higher BMI were associated with a higher likelihood of a recorded long COVID diagnosis, whereas no relationship was seen with glycaemic control.
- Extrapolation of overall 0.5% prevalence to the Greater Manchester population gave an estimated 9950 people aged > 25 years with long COVID.
IN PRACTICE:
“Long COVID services in England are based on an assessment and treatment model…These post-acute COVID services provide access to specialist diagnosis, treatment and rehabilitation. This paper is of relevance the focus of these services,” the authors wrote. “There remains an imperative for continuing awareness of long COVID as a differential diagnosis for multi-system symptomatic presentation in the context of a past acute COVID-19 infection,” they added.
SOURCE:
The study was conducted by Adrian H. Heald, of The University of Manchester, Manchester, UK, and Salford Royal Hospital, Salford, UK, and colleagues and published online on April 17, 2024, in the Lancet eClinicalMedicine.
LIMITATIONS:
Possible data coding errors. There was no information on symptoms or other information such as BMI in those without diabetes. Some with long COVID may not have had a positive COVID-19 test. Possible survivor bias.
DISCLOSURES:
The study was supported by the NIHR Applied Research Collaboration Greater Manchester and the NIHR Manchester Biomedical Research Centre. The authors reported no conflicts of interest.
Source link : https://www.medscape.com/s/viewarticle/long-covid-rates-elevated-men-type-2-diabetes-2024a10007mx?src=rss
Author :
Publish date : 2024-04-24 13:00:00
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